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Best GLP-1 programs of 2026.

Compare leading GLP-1 weight loss programs and find the one that fits your goals and budget.

Medically reviewed by Christopher Stephenson, MDUpdated Sep 23, 2026

The ranking

  1. 2

    Embody

    Limited time: lock in $69/mo pricing
    • Compounded semaglutide $69/mo
    • Compounded tirzepatide $119/mo
    • Same price at every dose, no hidden fees
    • Free shipping to your door, arrives in 1 to 2 days
    9.4Excellent
    Ratings reflect our editorial assessment of medical oversight, medication sourcing, pricing, support and fulfillment, and are reviewed regularly. How we rate
    Visit Embody
  2. 3

    SnagRx

    Flat pricing: $69/month
    • Compounded semaglutide from $69/mo
    • Compounded tirzepatide from $119/mo
    • Price never increases as your dose goes up
    • Includes online visit, medication and 1 to 2 day shipping
    9.2Excellent
    Ratings reflect our editorial assessment of medical oversight, medication sourcing, pricing, support and fulfillment, and are reviewed regularly. How we rate
    Visit SnagRx
  3. 4

    Ro

    • Free insurance coverage checker, no card needed
    • Access to the Wegovy pill, if prescribed
    • FDA approved GLP-1s at the lowest prices available
    • Dedicated insurance concierge to fight for coverage
    9.0Very good
    Ratings reflect our editorial assessment of medical oversight, medication sourcing, pricing, support and fulfillment, and are reviewed regularly. How we rate
    Visit Ro
  4. 5

    MEDVi

    • Plans start at $179 first month, no insurance required
    • HSA and FSA approved, with unlimited 24/7 medical support
    • Patients lose an average of 18% of body weight
    8.8Very good
    Ratings reflect our editorial assessment of medical oversight, medication sourcing, pricing, support and fulfillment, and are reviewed regularly. How we rate
    Visit MEDVi

Ratings reflect our editorial assessment of medical oversight, medication sourcing, pricing, support and fulfillment, and are reviewed regularly. How we rate

How GLP-1 medications support weight loss.

01What they are

What are GLP-1 medications?

A smiling woman with silver hair holding a GLP-1 injection pen, against a citrus background

GLP-1 receptor agonists mimic a hormone your body already makes. Semaglutide acts on the GLP-1 receptor alone; tirzepatide acts on GLP-1 and GIP receptors together. Both come as FDA approved brands and as compounded versions made by licensed pharmacies at a lower cash price.

  • Reduces appetite and slows how fast the stomach empties
  • Wegovy and Zepbound are FDA approved for weight management
  • Compounded versions cost less in cash and are not FDA approved

02The evidence

What do the studies show?

A smiling woman in a white top, against a pale grey background

The two largest trials put semaglutide at about 15% of body weight lost over 68 weeks and tirzepatide at up to about 21% over 72 weeks. Results vary with the dose and how long you stay on treatment, and most of the loss returns within a year of stopping.

  • About 15% of body weight lost on semaglutide over 68 weeks
  • Up to about 21% on the highest dose of tirzepatide over 72 weeks
  • Most of it returns within a year of stopping treatment

03Choosing

How do you choose a program?

Two fingers holding a small round white tablet, against a sage background

If your insurance covers brand-name medication, start with a program that handles the prior authorization. If you are paying cash, a flat monthly price that includes the medication is the number to compare. The programs above are rated on exactly those points.

  • A licensed clinician reviews your intake and stays involved
  • One monthly price that includes the medication
  • Cancel any time, with the terms in plain sight

The top three, in detail.

  1. Provider review

    WellMedr

    9.8Outstanding

    WellMedr pairs personalized compounded GLP-1 weight loss treatment with unlimited clinician messaging and progress tracking, all managed online.

    • Compounded semaglutide plans from $49/mo for life
    • Compounded tirzepatide plans from $89/mo for life
    • Care platform that tracks your progress
    • Provider review and unlimited clinician support
    1. Getting started

      A short online health assessment is reviewed by a U.S. licensed clinician, who determines eligibility and builds a personalized treatment plan before any medication ships.

    2. Shipping and support

      Medication ships free and discreetly to your door, with on-time refills before you run out. Members get unlimited messaging with a nursing team and a real-time care platform for dosing guidance.

    3. What it costs

      Compounded semaglutide starts at $49 a month and compounded tirzepatide at $89 a month on a 12-month plan, with pricing locked in for life. No insurance required.

    4. Flexibility and terms

      Plans are available month to month with no long-term contract. Patients can change plans or cancel at any time.

  2. Provider review

    Embody

    9.4Excellent

    Embody offers customized compounded semaglutide and tirzepatide prescribed by licensed providers, with 24/7 care team access and no membership fees or office visits.

    • Compounded semaglutide $69/mo
    • Compounded tirzepatide $119/mo
    • Same price at every dose, no hidden fees
    • Free shipping to your door, arrives in 1 to 2 days
    1. Getting started

      A short online health questionnaire, reviewed by a licensed provider who decides whether treatment is appropriate.

    2. Shipping and support

      Free delivery from U.S. pharmacy partners, typically in 1 to 2 days. A nursing team handles refills, dosing questions and ongoing support.

    3. What it costs

      $69 a month for compounded semaglutide and $119 a month for compounded tirzepatide on a 12-month program, with no membership fee.

    4. Flexibility and terms

      Month to month, with no long-term contract. Cancel any time before your next shipment to avoid the next charge.

  3. Provider review

    SnagRx

    9.2Excellent

    SnagRx keeps one flat monthly price that never rises with your dose, with the online visit, the medication and shipping all included.

    • Compounded semaglutide from $69/mo
    • Compounded tirzepatide from $119/mo
    • Price never increases as your dose goes up
    • Includes online visit, medication and 1 to 2 day shipping
    1. Getting started

      A short online intake, with a licensed provider review typically within 24 hours.

    2. Shipping and support

      Free delivery from U.S. licensed 503A compounding pharmacies, generally in 1 to 2 days, and same day if ordered before 2pm Central. The care team is reachable through the patient portal for refills and dosing questions.

    3. What it costs

      Compounded semaglutide from $69 a month and compounded tirzepatide from $119 a month, including the visit, the medication and shipping.

    4. Flexibility and terms

      Month to month with no long-term contract, and a refund for the unused portion of a term if a provider decides you no longer qualify.

Questions, answered.

Are GLP-1 medications safe for weight loss?

FDA approved GLP-1s such as Wegovy and Zepbound are approved for chronic weight management and are generally well tolerated.

The most common side effects are nausea, vomiting, diarrhea and constipation, and they carry a boxed warning about a rare thyroid tumor risk seen in animal studies.

Compounded versions have not been reviewed by the FDA.

A licensed clinician should decide whether treatment is right for you.

How much weight can I expect to lose with GLP-1 treatment?

In clinical trials, semaglutide produced an average loss of about 15% of body weight over 68 weeks, and tirzepatide up to about 21% at the highest dose over 72 weeks.

Individual results vary with the medication, the dose, how long you stay on treatment and lifestyle changes.

Does insurance cover GLP-1 medications for weight loss?

Sometimes, for brand-name medication, and usually only after a prior authorization that checks your body mass index and related conditions.

Compounded medication is almost never covered.

Several of the programs above will check your coverage before you pay for a consult.

How do I choose between different GLP-1 providers?

Compare what the monthly price includes, whether the medication is brand-name or compounded, how quickly a licensed clinician reviews your intake, what support you get between refills, and the cancellation terms.

The highlights on each card above cover those points.

What is the difference between telemedicine and in-person GLP-1 treatment?

The prescription is the same.

Telehealth programs review your health history online, often within a day, and ship the medication to your door, usually at a lower cash price.

An in-person clinic can examine you and run labs on site, which some patients prefer.

How long do I need to take GLP-1 medications?

GLP-1s are intended for ongoing use.

In the semaglutide extension study, people who stopped regained most of the weight within a year.

How long you stay on treatment is a decision to make with your clinician.

Our #1 pick

Ready to start? WellMedr is our top pick.

The lowest advertised price on the page, with unlimited clinician messaging.

Our #1 pick

WellMedr

9.8Outstanding

Visit WellMedr